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Event Date/Time Venue/City  
Houston Astros at Toronto Blue Jays Sun, May 1, 2022
TBA		 Rogers Centre
Toronto, ON
Seattle Mariners at Houston Astros Mon, May 2, 2022
TBA		 Minute Maid Park
Houston, TX
Seattle Mariners at Houston Astros Tue, May 3, 2022
TBA		 Minute Maid Park
Houston, TX
Seattle Mariners at Houston Astros Wed, May 4, 2022
TBA		 Minute Maid Park
Houston, TX
Detroit Tigers at Houston Astros Thu, May 5, 2022
TBA		 Minute Maid Park
Houston, TX
Detroit Tigers at Houston Astros Sat, May 7, 2022
TBA		 Minute Maid Park
Houston, TX
Detroit Tigers at Houston Astros Sun, May 8, 2022
TBA		 Minute Maid Park
Houston, TX
Houston Astros at Minnesota Twins Tue, May 10, 2022
TBA		 Target Field
Minneapolis, MN
Houston Astros at Minnesota Twins Wed, May 11, 2022
TBA		 Target Field
Minneapolis, MN
Houston Astros at Minnesota Twins Thu, May 12, 2022
TBA		 Target Field
Minneapolis, MN
Houston Astros at Washington Nationals Fri, May 13, 2022
TBA		 Nationals Park
Washington, DC
Houston Astros at Washington Nationals Sat, May 14, 2022
TBA		 Nationals Park
Washington, DC
Houston Astros at Washington Nationals Sun, May 15, 2022
TBA		 Nationals Park
Washington, DC
Houston Astros at Boston Red Sox Mon, May 16, 2022
TBA		 Fenway Park
Boston, MA
Houston Astros at Boston Red Sox Tue, May 17, 2022
TBA		 Fenway Park
Boston, MA
Houston Astros at Boston Red Sox Wed, May 18, 2022
TBA		 Fenway Park
Boston, MA
Texas Rangers at Houston Astros Thu, May 19, 2022
TBA		 Minute Maid Park
Houston, TX
Texas Rangers at Houston Astros Sun, May 22, 2022
TBA		 Minute Maid Park
Houston, TX
Cleveland Guardians at Houston Astros Mon, May 23, 2022
TBA		 Minute Maid Park
Houston, TX
Cleveland Guardians at Houston Astros Tue, May 24, 2022
TBA		 Minute Maid Park
Houston, TX
Houston Astros at Seattle Mariners Fri, May 27, 2022
TBA		 T-Mobile Park
Seattle, WA
Houston Astros at Seattle Mariners Sat, May 28, 2022
TBA		 T-Mobile Park
Seattle, WA
Houston Astros at Seattle Mariners Sun, May 29, 2022
TBA		 T-Mobile Park
Seattle, WA
Houston Astros at Oakland Athletics Mon, May 30, 2022
TBA		 RingCentral Coliseum
Oakland, CA
Houston Astros at Oakland Athletics Tue, May 31, 2022
TBA		 RingCentral Coliseum
Oakland, CA
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